Universities in Colorado and Wyoming have generated tens of billions of dollars in economic activity over the years and will no doubt do so for years to come, even as prospects for state and federal funding dim.

Technologies developed at the universities – from biotechnology to renewable-energy solutions – have formed the basis of scores of new companies in just the past few years.

Revenue from royalties based on the sales of products protected by university patents, including legal settlements, totals more than $100 million.

The University of Colorado alone is among the top 10 universities nationwide in the number of companies created.

These universities provide essential research and train a large number of scientists and engineers. That, of course, is why federal funding is crucial for them.

At CSU, for example, more than 80 percent of the university's research funding comes from federal agencies such as the National Science Foundation and National Institutes of Health, said Bill Farland, vice president of research.

The rest of its funding comes from the private sector and foundations; a small amount comes from the university itself to match some of the grants